Version 5.4
| Bos taurus Gene: CD207 | |||||
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| Summary | |||||
| InnateDB Gene | IDBG-631820.3 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | CD207 | ||||
| Gene Name | Uncharacterized protein | ||||
| Synonyms | |||||
| Species | Bos taurus | ||||
| Ensembl Gene | ENSBTAG00000004562 | ||||
| Encoded Proteins |
CD207 molecule, langerin
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| Protein Structure | |||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||
| Entrez Gene | |||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116031:
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010] |
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| Gene Information | |||||
| Type | Protein coding | ||||
| Genomic Location | Chromosome 11:13572118-13576257 | ||||
| Strand | Forward strand | ||||
| Band | |||||
| Transcripts |
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| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||
| NETPATH | |||||
| REACTOME |
Cross-presentation of soluble exogenous antigens (endosomes) pathway
Antigen processing-Cross presentation pathway
Adaptive Immune System pathway
Immune System pathway
Class I MHC mediated antigen processing & presentation pathway
Class I MHC mediated antigen processing & presentation pathway
Immune System pathway
Cross-presentation of soluble exogenous antigens (endosomes) pathway
Antigen processing-Cross presentation pathway
Adaptive Immune System pathway
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| KEGG | |||||
| INOH | |||||
| PID NCI | |||||
| Cross-References | |||||
| SwissProt | |||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | |||||
| UniGene | Bt.61803 | ||||
| RefSeq | XM_002691221 XM_588243 | ||||
| HUGO | |||||
| OMIM | |||||
| CCDS | |||||
| HPRD | |||||
| IMGT | |||||
| EMBL | |||||
| GenPept | |||||
| RNA Seq Atlas | |||||