Bos taurus Gene: NUDT21
Summary
InnateDB Gene IDBG-632047.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUDT21
Gene Name Cleavage and polyadenylation specificity factor subunit 5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010207
Encoded Proteins
Cleavage and polyadenylation specificity factor subunit 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167005:
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is one subunit of a cleavage factor required for 3\' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3\' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:24267849-24282456
Strand Forward strand
Band
Transcripts
ENSBTAT00000013467 ENSBTAP00000013467
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 77 interaction(s) predicted by orthology.
Predicted by orthology
Total 77 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0017091 AU-rich element binding
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006378 mRNA polyadenylation
GO:0006397 mRNA processing
GO:0051262 protein tetramerization
Cellular Component
GO:0005634 nucleus
GO:0005813 centrosome
GO:0005849 mRNA cleavage factor complex
GO:0042382 paraspeckles
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
RNA Polymerase II Transcription pathway
Cleavage of Growing Transcript in the Termination Region pathway
mRNA Splicing - Major Pathway pathway
mRNA Splicing pathway
Processing of Capped Intronless Pre-mRNA pathway
mRNA 3'-end processing pathway
RNA Polymerase II Transcription Termination pathway
Gene Expression pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Processing of Intronless Pre-mRNAs pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Processing of Intronless Pre-mRNAs pathway
mRNA 3'-end processing pathway
mRNA Splicing - Major Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Cleavage of Growing Transcript in the Termination Region pathway
RNA Polymerase II Transcription Termination pathway
RNA Polymerase II Transcription pathway
Processing of Capped Intronless Pre-mRNA pathway
mRNA Splicing pathway
Gene Expression pathway
mRNA 3'-end processing pathway
mRNA Splicing pathway
Processing of Capped Intronless Pre-mRNA pathway
Processing of Intronless Pre-mRNAs pathway
RNA Polymerase II Transcription Termination pathway
Cleavage of Growing Transcript in the Termination Region pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
KEGG
mRNA surveillance pathway pathway
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q3ZCA2
TrEMBL
UniProt Splice Variant
Entrez Gene 518859
UniGene Bt.103726 Bt.49427
RefSeq NM_001035331
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102697
GenPept AAI02698
RNA Seq Atlas 518859