Mus musculus Gene: Nudt21
Summary
InnateDB Gene IDBG-181366.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nudt21
Gene Name nudix (nucleoside diphosphate linked moiety X)-type motif 21
Synonyms 25kDa; 3110048P04Rik; 5730530J16Rik; AU014860; AW549947; Cpsf5
Species Mus musculus
Ensembl Gene ENSMUSG00000031754
Encoded Proteins
nudix (nucleoside diphosphate linked moiety X)-type motif 21
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167005:
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is one subunit of a cleavage factor required for 3\' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3\' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:94017770-94037021
Strand Reverse strand
Band C5
Transcripts
ENSMUST00000034204 ENSMUSP00000034204
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 81 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 81 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0017091 AU-rich element binding
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006378 mRNA polyadenylation
GO:0006397 mRNA processing
GO:0051262 protein tetramerization
Cellular Component
GO:0005634 nucleus
GO:0005813 centrosome
GO:0005849 mRNA cleavage factor complex
GO:0042382 paraspeckles
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
mRNA 3'-end processing pathway
mRNA Splicing pathway
Processing of Capped Intronless Pre-mRNA pathway
Processing of Intronless Pre-mRNAs pathway
RNA Polymerase II Transcription Termination pathway
Cleavage of Growing Transcript in the Termination Region pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
KEGG
mRNA surveillance pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Processing of Intronless Pre-mRNAs pathway
mRNA 3'-end processing pathway
mRNA Splicing - Major Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Cleavage of Growing Transcript in the Termination Region pathway
RNA Polymerase II Transcription Termination pathway
RNA Polymerase II Transcription pathway
Processing of Capped Intronless Pre-mRNA pathway
mRNA Splicing pathway
Gene Expression pathway
RNA Polymerase II Transcription pathway
Cleavage of Growing Transcript in the Termination Region pathway
mRNA Splicing - Major Pathway pathway
mRNA Splicing pathway
Processing of Capped Intronless Pre-mRNA pathway
mRNA 3'-end processing pathway
RNA Polymerase II Transcription Termination pathway
Gene Expression pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Processing of Intronless Pre-mRNAs pathway
KEGG
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q9CQF3
TrEMBL Q9CZQ0
UniProt Splice Variant
Entrez Gene 68219
UniGene Mm.354445 Mm.381360 Mm.423992
RefSeq NM_026623
OMIM
CCDS CCDS40433
HPRD
IMGT
MGI ID MGI:1915469
MGI Symbol Nudt21
EMBL AK011688 AK012308 AK019433 AK146419 AK147061 AK160147 BC008270 BC090834
GenPept AAH08270 AAH90834 BAB27778 BAB28154 BAB31718 BAE27154 BAE27645 BAE35655
RNA Seq Atlas 68219