Version 5.4
Bos taurus Gene: BT.20583
Summary
InnateDB Gene IDBG-632079.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.20583
Gene Name prefoldin subunit 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017265
Encoded Proteins
IDBP-683665
prefoldin subunit 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155959:
The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. Because it functions as a chaperone protein, it is suspected that it may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. [provided by RefSeq, Jul 2008]
The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. Because it functions as a chaperone protein, it is suspected that it may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:38609347-38633977
Strand Reverse strand
Band
Transcripts
ENSBTAT00000022946 ENSBTAP00000022946
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
Cellular Component
GO:0005737 cytoplasm
GO:0016272 prefoldin complex
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000155959
View Gene Order
ENSMUSG00000031197
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_16936
Prefoldin mediated transfer of substrate to CCT/TriC pathway
REACT_16952
Protein folding pathway
REACT_17004
Chaperonin-mediated protein folding pathway
REACT_17015
Metabolism of proteins pathway
REACT_17029
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
REACT_258900
Chaperonin-mediated protein folding pathway
REACT_247926
Metabolism of proteins pathway
REACT_260833
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
REACT_245534
Protein folding pathway
REACT_245663
Prefoldin mediated transfer of substrate to CCT/TriC pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G5E5K1
UniProt Splice Variant
Entrez Gene 508727
UniGene Bt.20583
RefSeq NM_001038516
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02070017 DAAA02070018
GenPept
RNA Seq Atlas 508727

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca