InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: EIF2B1

Summary

InnateDB Gene

IDBG-632177.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EIF2B1

Gene Name

Translation initiation factor eIF-2B subunit alpha

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000007269

Encoded Proteins

IDBP-683772

Translation initiation factor eIF-2B subunit alpha

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111361:
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Oct 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:54297406-54308318

Strand

Forward strand

Band

Transcripts

ENSBTAT00000009560

ENSBTAP00000009560

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003743	translation initiation factor activity
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005515	protein binding

Biological Process

GO:0006412	translation
GO:0006413	translational initiation
GO:0006446	regulation of translational initiation
GO:0014003	oligodendrocyte development
GO:0043547	positive regulation of GTPase activity
GO:0044237	cellular metabolic process
GO:0051716	cellular response to stimulus