Bos taurus Gene: GALNT6
Summary
InnateDB Gene IDBG-632281.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GALNT6
Gene Name polypeptide N-acetylgalactosaminyltransferase 6
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017943
Encoded Proteins
polypeptide N-acetylgalactosaminyltransferase 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139629:
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:28576320-28615499
Strand Forward strand
Band
Transcripts
ENSBTAT00000023861 ENSBTAP00000023861
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity
GO:0016740 transferase activity
GO:0016757 transferase activity, transferring glycosyl groups
GO:0046872 metal ion binding
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
O-linked glycosylation of mucins pathway
Post-translational protein modification pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-linked glycosylation of mucins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
O-linked glycosylation pathway
KEGG
Mucin type O-Glycan biosynthesis pathway
Mucin type O-Glycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A6H6Z5
UniProt Splice Variant
Entrez Gene 506903
UniGene Bt.1639
RefSeq NM_001015534 XM_005206272 XM_005206273 XM_005206274 XM_005206275 XM_005206276
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC146055 DAAA02012907 DAAA02012908 DAAA02012909
GenPept AAI46056
RNA Seq Atlas 506903