InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PLXNB3

Summary

InnateDB Gene

IDBG-632346.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PLXNB3

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000010146

Encoded Proteins

IDBP-684034

plexin B3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198753:
The protein encoded by this gene is a member of the plexin family. It functions as a receptor for semaphorin 5A, and plays a role in axon guidance, invasive growth and cell migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:39898642-39910712

Strand

Forward strand

Band

Transcripts

ENSBTAT00000013391

ENSBTAP00000013391

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005515	protein binding
GO:0017154	semaphorin receptor activity
GO:0019904	protein domain specific binding
GO:0051022	Rho GDP-dissociation inhibitor binding

Biological Process

GO:0001938	positive regulation of endothelial cell proliferation
GO:0007162	negative regulation of cell adhesion
GO:0007165	signal transduction
GO:0007275	multicellular organismal development
GO:0030336	negative regulation of cell migration
GO:0034260	negative regulation of GTPase activity
GO:0050918	positive chemotaxis
GO:0060326	cell chemotaxis
GO:0071526	semaphorin-plexin signaling pathway