InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: AQP2

Summary

InnateDB Gene

IDBG-632459.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AQP2

Gene Name

Aquaporin-2

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000008374

Encoded Proteins

IDBP-684070

Aquaporin-2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167580:
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:30097668-30103142

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000011024

ENSBTAP00000011024

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005372	water transmembrane transporter activity
GO:0015168	glycerol transmembrane transporter activity
GO:0015250	water channel activity

Biological Process

GO:0003097	renal water transport
GO:0006810	transport
GO:0006833	water transport
GO:0015793	glycerol transport
GO:0042631	cellular response to water deprivation
GO:0071280	cellular response to copper ion
GO:0071288	cellular response to mercury ion
GO:0072205	metanephric collecting duct development

Cellular Component

GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane
GO:0016324	apical plasma membrane
GO:0030659	cytoplasmic vesicle membrane
GO:0031410	cytoplasmic vesicle
GO:0055037	recycling endosome
GO:0070062	extracellular vesicular exosome