Version 5.4
Bos taurus Gene: KATNB1
Summary
InnateDB Gene IDBG-632610.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KATNB1
Gene Name katanin p80 WD40-containing subunit B1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001848
Encoded Proteins
IDBP-684252
katanin p80 WD40-containing subunit B1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140854:
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:25785516-25803400
Strand Forward strand
Band
Transcripts
ENSBTAT00000053556 ENSBTAP00000051325
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0008568 microtubule-severing ATPase activity
GO:0045502 dynein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006200 ATP catabolic process
GO:0007026 negative regulation of microtubule depolymerization
GO:0007049 cell cycle
GO:0007067 mitotic nuclear division
GO:0007079 mitotic chromosome movement towards spindle pole
GO:0031117 positive regulation of microtubule depolymerization
GO:0051013 microtubule severing
GO:0051301 cell division
Cellular Component
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005819 spindle
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0008352 katanin complex
GO:0016020 membrane
GO:0030424 axon
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000140854
View Gene Order
ENSMUSG00000031787
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.3402
RefSeq NM_001101909 XM_005218502
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca