Version 5.4
Bos taurus Gene: PRPH
Summary
InnateDB Gene IDBG-632615.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRPH
Gene Name Peripherin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017864
Encoded Proteins
IDBP-684250
Peripherin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135406:
This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:30688660-30692263
Strand Reverse strand
Band
Transcripts
ENSBTAT00000023744 ENSBTAP00000023744
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
GO:0045104 intermediate filament cytoskeleton organization
Cellular Component
GO:0005882 intermediate filament
GO:0005883 neurofilament
GO:0016020 membrane
GO:0030424 axon
GO:0042622 photoreceptor outer segment membrane
GO:0044299 C-fiber
GO:0045098 type III intermediate filament
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000135406
View Gene Order
ENSMUSG00000023484
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05014
Amyotrophic lateral sclerosis (ALS) pathway
mmu05014
Amyotrophic lateral sclerosis (ALS) pathway
INOH
PID NCI
Cross-References
SwissProt A6QQJ3
TrEMBL
UniProt Splice Variant
Entrez Gene 510082
UniGene Bt.30375
RefSeq NM_001102378 XM_005206288
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149862
GenPept AAI49863
RNA Seq Atlas 510082

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca