Version 5.4
Bos taurus Gene: SLC39A1
Summary
InnateDB Gene IDBG-632641.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC39A1
Gene Name Zinc transporter ZIP1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011284
Encoded Proteins
IDBP-684269
Zinc transporter ZIP1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143570:
This gene encodes a member of the zinc-iron permease family. The encoded protein is localized to the cell membrane and acts as a zinc uptake transporter. This gene has been linked to prostate cancer, breast cancer, and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:16530784-16534816
Strand Forward strand
Band
Transcripts
ENSBTAT00000034015 ENSBTAP00000033917
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005385 zinc ion transmembrane transporter activity
GO:0046873 metal ion transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006829 zinc ion transport
GO:0030001 metal ion transport
GO:0055085 transmembrane transport
GO:0071577 zinc ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000143570
View Gene Order
ENSMUSG00000052310
View Gene Order
Pathways
NETPATH
REACTOME
REACT_222460
SLC-mediated transmembrane transport pathway
REACT_208122
Zinc transporters pathway
REACT_221584
Metal ion SLC transporters pathway
REACT_223103
Transmembrane transport of small molecules pathway
REACT_219894
Zinc influx into cells by the SLC39 gene family pathway
REACT_212003
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20603
Zinc influx into cells by the SLC39 gene family pathway
REACT_20547
Metal ion SLC transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_20530
Zinc transporters pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_217615
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_198240
Zinc influx into cells by the SLC39 gene family pathway
REACT_243781
Zinc transporters pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_251299
Metal ion SLC transporters pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q3SYU3
TrEMBL
UniProt Splice Variant
Entrez Gene 530352
UniGene Bt.31629
RefSeq NM_001035381 XM_005203724
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103384
GenPept AAI03385
RNA Seq Atlas 530352

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca