Version 5.4
Bos taurus Gene: BT.56220
Summary
InnateDB Gene IDBG-632672.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.56220
Gene Name thioredoxin domain-containing protein 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015353
Encoded Proteins
IDBP-684303
thioredoxin domain containing 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000086288:
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.[provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:49959050-49995977
Strand Forward strand
Band
Transcripts
ENSBTAT00000047146 ENSBTAP00000044371
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006165 nucleoside diphosphate phosphorylation
GO:0006183 GTP biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0045454 cell redox homeostasis
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000086288
View Gene Order
ENSMUSG00000041138
View Gene Order
Cross-References
SwissProt
TrEMBL F1MTN9
UniProt Splice Variant
Entrez Gene 518005
UniGene Bt.56220
RefSeq NM_001046235 XM_005205412 XM_005205413 XM_005205414 XM_005205415 XM_005205416
HUGO HGNC:16473
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02010600 DAAA02010601
GenPept
RNA Seq Atlas 518005

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca