Version 5.4
Bos taurus Gene: SEC23A
Summary
InnateDB Gene IDBG-632736.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEC23A
Gene Name Protein transport protein Sec23A
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003708
Encoded Proteins
IDBP-684378
Protein transport protein Sec23A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100934:
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:49489517-49555507
Strand Reverse strand
Band
Transcripts
ENSBTAT00000004831 ENSBTAP00000004831
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.
Predicted by orthology
Total 46 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0006888 ER to Golgi vesicle-mediated transport
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0030127 COPII vesicle coat
GO:0030134 ER to Golgi transport vesicle
GO:0030868 smooth endoplasmic reticulum membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000100934
View Gene Order
ENSMUSG00000020986
View Gene Order
Pathways
NETPATH
REACTOME
REACT_218212
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
REACT_214728
Transport to the Golgi and subsequent modification pathway
REACT_212672
Class I MHC mediated antigen processing & presentation pathway
REACT_213138
Immune System pathway
REACT_223866
Asparagine N-linked glycosylation pathway
REACT_211133
MHC class II antigen presentation pathway
REACT_213782
Metabolism of proteins pathway
REACT_214405
Post-translational protein modification pathway
REACT_219933
Metabolism of lipids and lipoproteins pathway
REACT_225088
ER to Golgi Transport pathway
REACT_219139
Metabolism pathway
REACT_220924
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_214469
Adaptive Immune System pathway
REACT_208174
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
REACT_213260
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75795
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
REACT_121399
MHC class II antigen presentation pathway
REACT_12507
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_25046
Transport to the Golgi and subsequent modification pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_147797
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_22161
Post-translational protein modification pathway
REACT_11203
ER to Golgi Transport pathway
REACT_17015
Metabolism of proteins pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
REACT_111217
Metabolism pathway
REACT_11123
Membrane Trafficking pathway
REACT_205304
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_206143
Transport to the Golgi and subsequent modification pathway
REACT_198968
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
REACT_209837
Membrane Trafficking pathway
REACT_188937
Metabolism pathway
REACT_230745
Immune System pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_196550
MHC class II antigen presentation pathway
REACT_203486
ER to Golgi Transport pathway
REACT_237472
Asparagine N-linked glycosylation pathway
REACT_229531
Adaptive Immune System pathway
REACT_246972
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt A2VDL8
TrEMBL F1MVW5
UniProt Splice Variant
Entrez Gene 533994
UniGene Bt.21115 Bt.69980
RefSeq NM_001081604 XM_005222099 XM_005222100 XM_005222101
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133300 DAAA02052820 DAAA02052821
GenPept AAI33301
RNA Seq Atlas 533994

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca