Version 5.4
Bos taurus Gene: SCAF11
Summary
InnateDB Gene IDBG-633195.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCAF11
Gene Name protein SCAF11
Synonyms SFRS2IP; SRSF2IP
Species Bos taurus
Ensembl Gene ENSBTAG00000001810
Encoded Proteins
IDBP-684902
SR-related CTD-associated factor 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 22895188
[Homo sapiens] Caspase-11 (SCAF11) increases susceptibility to Salmonella infection in the absence of caspase-1. (Demonstrated in mouse)
PMID 22895188
[Mus musculus] Caspase-11 (SCAF11) increases susceptibility to Salmonella infection in the absence of caspase-1.
PMID 23348507
[Mus musculus] SCAF11 (Caspase 11) is required for innate surveillance against bacteria that escape the vacuole.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139218:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:34430403-34480031
Strand Forward strand
Band
Transcripts
ENSBTAT00000002366 ENSBTAP00000002366
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000375 RNA splicing, via transesterification reactions
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000139218
View Gene Order
ENSMUSG00000033228
View Gene Order
Cross-References
SwissProt
TrEMBL F1N2H2
UniProt Splice Variant
Entrez Gene 538632
UniGene Bt.39641
RefSeq NM_001205567 XM_005206394
HUGO HGNC:10784
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02013014
GenPept
RNA Seq Atlas 538632

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca