Version 5.4
| Bos taurus Gene: SERPINA7 | |||||
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| Summary | |||||
| InnateDB Gene | IDBG-633237.2 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | SERPINA7 | ||||
| Gene Name | thyroxine-binding globulin precursor | ||||
| Synonyms | |||||
| Species | Bos taurus | ||||
| Ensembl Gene | ENSBTAG00000047655 | ||||
| Encoded Proteins |
thyroxine-binding globulin precursor
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| Protein Structure | |||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||
| Entrez Gene | |||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123561:
There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.[provided by RefSeq, Jun 2012] There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3\'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.[provided by RefSeq, Jun 2012] |
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| Gene Information | |||||
| Type | Protein coding | ||||
| Genomic Location | Chromosome X:53582627-53588080 | ||||
| Strand | Reverse strand | ||||
| Band | |||||
| Transcripts |
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| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Cross-References | |||||
| SwissProt | |||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | |||||
| UniGene | Bt.49228 | ||||
| RefSeq | NM_174668 XM_005227754 | ||||
| HUGO | |||||
| OMIM | |||||
| CCDS | |||||
| HPRD | |||||
| IMGT | |||||
| EMBL | |||||
| GenPept | |||||
| RNA Seq Atlas | |||||
| Transcript Frequencies | |||||
| Tag Count based mRNA-Abundances across 87 different Tissues (TPM).
Based on Data from Bovine Gene Atlas |
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