InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CERS2

Summary

InnateDB Gene

IDBG-633278.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CERS2

Gene Name

Ceramide synthase 2

Synonyms

LASS2

Species

Bos taurus

Ensembl Gene

ENSBTAG00000000099

Encoded Proteins

IDBP-684981

Ceramide synthase 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143418:
This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:19835017-19843638

Strand

Forward strand

Band

Transcripts

ENSBTAT00000000109

ENSBTAP00000000109

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.

Predicted by orthology
Total	46 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0050291	sphingosine N-acyltransferase activity

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006629	lipid metabolic process
GO:0030148	sphingolipid biosynthetic process
GO:0046513	ceramide biosynthetic process

Cellular Component

GO:0005634	nucleus
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031965	nuclear membrane