Version 5.4
Bos taurus Gene: ADAMTS20
Summary
InnateDB Gene IDBG-633324.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAMTS20
Gene Name A disintegrin and metalloproteinase with thrombospondin motifs 20 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000395
Encoded Proteins
IDBP-685052
ADAM metallopeptidase with thrombospondin type 1 motif, 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173157:
The protein encoded by this gene is a member of the ADAMTS family of zinc-dependent proteases. The encoded protein has a signal peptide that is cleaved to release the mature peptide, which is secreted and found in the extracellular matrix. This protein may be involved in tissue remodeling. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:37102590-37332440
Strand Forward strand
Band
Transcripts
ENSBTAT00000036986 ENSBTAP00000036833
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0009967 positive regulation of signal transduction
GO:0030198 extracellular matrix organization
GO:0043066 negative regulation of apoptotic process
GO:0045636 positive regulation of melanocyte differentiation
GO:0048070 regulation of developmental pigmentation
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000173157
View Gene Order
ENSMUSG00000022449
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22161
Post-translational protein modification pathway
REACT_200727
O-linked glycosylation pathway
REACT_17015
Metabolism of proteins pathway
REACT_200626
O-glycosylation of TSR domain-containing proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1B900
UniProt Splice Variant
Entrez Gene 536137
UniGene Bt.94723
RefSeq NM_001206093 XM_005206429
HUGO HGNC:17178
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02013044 DAAA02013045 DAAA02013046 DAAA02013047 DAAA02013048 DAAA02013049 DAAA02013050 DAAA02013051 DAAA02013052 DAAA02013053 DAAA02013054 DAAA02013055 DAAA02013056 DAAA02013057 DAAA02013058 DAAA02013059 DAAA02013060 DAAA02013061
GenPept
RNA Seq Atlas 536137

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca