Version 5.4
Bos taurus Gene: CNTN1
Summary
InnateDB Gene IDBG-633416.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNTN1
Gene Name contactin-1 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020679
Encoded Proteins
IDBP-685130
contactin-1 precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000018236:
The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:39998363-40264645
Strand Reverse strand
Band
Transcripts
ENSBTAT00000045515 ENSBTAP00000042896
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001948 glycoprotein binding
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0010628 positive regulation of gene expression
GO:0010765 positive regulation of sodium ion transport
GO:0010976 positive regulation of neuron projection development
GO:0021549 cerebellum development
GO:0031175 neuron projection development
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000018236
View Gene Order
ENSMUSG00000055022
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_3
Notch pathway
REACTOME
REACT_118614
Activated NOTCH1 Transmits Signal to the Nucleus pathway
REACT_160205
NOTCH2 Activation and Transmission of Signal to the Nucleus pathway
REACT_22312
Neurofascin interactions pathway
REACT_22205
L1CAM interactions pathway
REACT_111045
Developmental Biology pathway
REACT_160082
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
REACT_160214
Signaling by NOTCH1 in Cancer pathway
REACT_18266
Axon guidance pathway
REACT_160099
FBXW7 Mutants and NOTCH1 in Cancer pathway
REACT_111102
Signal Transduction pathway
REACT_118721
Signaling by NOTCH2 pathway
REACT_160301
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
REACT_160248
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
REACT_299
Signaling by NOTCH pathway
REACT_118859
Signaling by NOTCH1 pathway
REACT_160133
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
REACT_116125
Disease pathway
REACT_189085
Disease pathway
REACT_199382
Signaling by NOTCH1 pathway
REACT_199384
Activated NOTCH1 Transmits Signal to the Nucleus pathway
REACT_199412
Signaling by NOTCH2 pathway
REACT_199410
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
REACT_199411
NOTCH2 Activation and Transmission of Signal to the Nucleus pathway
REACT_199405
Signaling by NOTCH1 in Cancer pathway
REACT_199407
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
REACT_199406
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
REACT_199409
FBXW7 Mutants and NOTCH1 in Cancer pathway
REACT_199408
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
REACT_261444
Axon guidance pathway
REACT_219680
L1CAM interactions pathway
REACT_188576
Developmental Biology pathway
REACT_235102
Neurofascin interactions pathway
REACT_188257
Signal Transduction pathway
REACT_231152
Signaling by NOTCH pathway
KEGG
hsa04514
Cell adhesion molecules (CAMs) pathway
mmu04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
notch_pathway
Notch signaling pathway
Cross-References
SwissProt
TrEMBL A7E333 F1MVI0
UniProt Splice Variant
Entrez Gene 281705
UniGene Bt.349
RefSeq NM_174280
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151686 DAAA02013116 DAAA02013117 DAAA02013118 DAAA02013119
GenPept AAI51687
RNA Seq Atlas 281705

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca