Bos taurus Gene: AGRP
Summary
InnateDB Gene IDBG-633565.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AGRP
Gene Name agouti-related protein precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014556
Encoded Proteins
agouti-related protein precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159723:
This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:35205885-35206635
Strand Reverse strand
Band
Transcripts
ENSBTAT00000019347 ENSBTAP00000019347
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005184 neuropeptide hormone activity
Biological Process
GO:0007218 neuropeptide signaling pathway
GO:0008343 adult feeding behavior
GO:0009755 hormone-mediated signaling pathway
GO:0060259 regulation of feeding behavior
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005796 Golgi lumen
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Adipocytokine signaling pathway pathway
Adipocytokine signaling pathway pathway
INOH
PID NCI
Syndecan-3-mediated signaling events
Cross-References
SwissProt
TrEMBL D2CNK1
UniProt Splice Variant
Entrez Gene 280987
UniGene Bt.91
RefSeq NM_173983
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02046683 EU374211 EU374213
GenPept ACB72646 ACB72648
RNA Seq Atlas 280987