Bos taurus Gene: BCL9
Summary
InnateDB Gene IDBG-633778.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCL9
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002422
Encoded Proteins
B-cell CLL/lymphoma 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116128:
BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:22106734-22120933
Strand Reverse strand
Band
Transcripts
ENSBTAT00000003141 ENSBTAP00000003141
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008013 beta-catenin binding
Biological Process
GO:0014908 myotube differentiation involved in skeletal muscle regeneration
GO:0035019 somatic stem cell maintenance
GO:0035914 skeletal muscle cell differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060070 canonical Wnt signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
Wnt pathway
REACTOME
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
Signaling by WNT in cancer pathway
Signaling by Wnt pathway
deactivation of the beta-catenin transactivating complex pathway
Signal Transduction pathway
TCF dependent signaling in response to WNT pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
formation of the beta-catenin:TCF transactivating complex pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
Disease pathway
Disease pathway
Signaling by Wnt pathway
Signaling by WNT in cancer pathway
deactivation of the beta-catenin transactivating complex pathway
formation of the beta-catenin:TCF transactivating complex pathway
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
TCF dependent signaling in response to WNT pathway
Signal Transduction pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
KEGG
INOH
Wnt signaling pathway pathway
Wnt signaling pathway pathway
PID NCI
Regulation of nuclear beta catenin signaling and target gene transcription
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.26988
RefSeq XM_002686086 XM_002703865
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas