Bos taurus Gene: KCNMB4 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-633804.3 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | KCNMB4 | ||||||||||
Gene Name | calcium-activated potassium channel subunit beta-4 | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Gene | ENSBTAG00000003749 | ||||||||||
Encoded Proteins |
potassium large conductance calcium-activated channel, subfamily M, beta member 4
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135643:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 5:43266425-43347032 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | |||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME |
cGMP effects pathway
Nitric oxide stimulates guanylate cyclase pathway
Platelet homeostasis pathway
Ca2+ activated K+ channels pathway
Neuronal System pathway
Potassium Channels pathway
Hemostasis pathway
Platelet homeostasis pathway
Hemostasis pathway
Potassium Channels pathway
Ca2+ activated K+ channels pathway
cGMP effects pathway
Nitric oxide stimulates guanylate cyclase pathway
Neuronal System pathway
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KEGG |
Vascular smooth muscle contraction pathway
Vascular smooth muscle contraction pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | |||||||||||
UniGene | Bt.19643 | ||||||||||
RefSeq | NM_001192523 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | |||||||||||
GenPept | |||||||||||
RNA Seq Atlas | |||||||||||