Bos taurus Gene: STEAP4
Summary
InnateDB Gene IDBG-633820.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STEAP4
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002340
Encoded Proteins
STEAP family member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127954:
The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:72833497-72862043
Strand Reverse strand
Band
Transcripts
ENSBTAT00000030838 ENSBTAP00000030808
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008823 cupric reductase activity
GO:0052851 ferric-chelate reductase (NADPH) activity
Biological Process
GO:0015677 copper ion import
GO:0045444 fat cell differentiation
GO:0055114 oxidation-reduction process
GO:0097461 ferric iron import into cell
Cellular Component
GO:0005768 endosome
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL E1BJW2
UniProt Splice Variant
Entrez Gene 538861
UniGene Bt.56868
RefSeq XM_002686859 XM_583351
HUGO HGNC:21923
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02011023
GenPept
RNA Seq Atlas 538861