Version 5.4
Bos taurus Gene: ACOT7
Summary
InnateDB Gene IDBG-633873.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACOT7
Gene Name cytosolic acyl coenzyme A thioester hydrolase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021202
Encoded Proteins
IDBP-685614
cytosolic acyl coenzyme A thioester hydrolase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000097021:
This gene encodes a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA thioester of palmitoyl-CoA and other long-chain fatty acids. Decreased expression of this gene may be associated with mesial temporal lobe epilepsy. Alternatively spliced transcript variants encoding distinct isoforms with different subcellular locations have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:47827124-47934930
Strand Forward strand
Band
Transcripts
ENSBTAT00000028254 ENSBTAP00000028254
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000062 fatty-acyl-CoA binding
GO:0005515 protein binding
GO:0016290 palmitoyl-CoA hydrolase activity
GO:0036042 long-chain fatty acyl-CoA binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0009062 fatty acid catabolic process
GO:0015937 coenzyme A biosynthetic process
GO:0036114 medium-chain fatty-acyl-CoA catabolic process
GO:0036116 long-chain fatty-acyl-CoA catabolic process
GO:0051792 medium-chain fatty acid biosynthetic process
GO:1900535 palmitic acid biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0043005 neuron projection
GO:0044297 cell body
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000097021
View Gene Order
ENSMUSG00000028937
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa01040
Biosynthesis of unsaturated fatty acids pathway
hsa00062
Fatty acid elongation pathway
mmu01040
Biosynthesis of unsaturated fatty acids pathway
mmu00062
Fatty acid elongation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F6Q5U0 Q148I4
UniProt Splice Variant
Entrez Gene 514788
UniGene Bt.15725
RefSeq NM_001075682 XM_005217081
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118301 DAAA02043087
GenPept AAI18302
RNA Seq Atlas 514788

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca