Version 5.4
| Bos taurus Gene: NCBP1 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-633899.3 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | NCBP1 | ||||||||||||||||||
| Gene Name | nuclear cap binding protein subunit 1, 80kDa | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Bos taurus | ||||||||||||||||||
| Ensembl Gene | ENSBTAG00000009732 | ||||||||||||||||||
| Encoded Proteins |
nuclear cap-binding protein subunit 1
nuclear cap-binding protein subunit 1
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136937:
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008] The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5\' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3\'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 8:63298019-63335301 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | |||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
snRNP Assembly pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
SLBP independent Processing of Histone Pre-mRNAs pathway
Processing of Intronless Pre-mRNAs pathway
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs pathway
mRNA 3'-end processing pathway
mRNA Splicing - Major Pathway pathway
mRNA Splicing - Minor Pathway pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Transport of the SLBP independent Mature mRNA pathway
Transport of the SLBP Dependant Mature mRNA pathway
Transport of Mature mRNA Derived from an Intronless Transcript pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
mRNA Capping pathway
Cleavage of Growing Transcript in the Termination Region pathway
RNA Polymerase II Pre-transcription Events pathway
Formation of RNA Pol II elongation complex pathway
Formation of the Early Elongation Complex pathway
RNA Polymerase II Transcription Elongation pathway
Formation of HIV elongation complex in the absence of HIV Tat pathway
Formation of the HIV-1 Early Elongation Complex pathway
Formation of HIV-1 elongation complex containing HIV-1 Tat pathway
Tat-mediated elongation of the HIV-1 transcript pathway
Abortive elongation of HIV-1 transcript in the absence of Tat pathway
Transcription of the HIV genome pathway
Late Phase of HIV Life Cycle pathway
Nonsense-Mediated Decay (NMD) pathway
RNA Polymerase II Transcription Termination pathway
HIV Transcription Elongation pathway
RNA Polymerase II Transcription pathway
Transport of Mature Transcript to Cytoplasm pathway
HIV Life Cycle pathway
Metabolism of non-coding RNA pathway
Processing of Capped Intronless Pre-mRNA pathway
Transport of Mature mRNAs Derived from Intronless Transcripts pathway
HIV Infection pathway
mRNA Splicing pathway
Gene Expression pathway
Disease pathway
mRNA 3'-end processing pathway
Formation of the Early Elongation Complex pathway
Transport of Mature Transcript to Cytoplasm pathway
mRNA Splicing pathway
SLBP independent Processing of Histone Pre-mRNAs pathway
mRNA Splicing - Minor Pathway pathway
Processing of Capped Intronless Pre-mRNA pathway
Metabolism of non-coding RNA pathway
Nonsense-Mediated Decay (NMD) pathway
Formation of RNA Pol II elongation complex pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Processing of Intronless Pre-mRNAs pathway
RNA Polymerase II Transcription Termination pathway
RNA Polymerase II Transcription Elongation pathway
Cleavage of Growing Transcript in the Termination Region pathway
RNA Polymerase II Pre-transcription Events pathway
snRNP Assembly pathway
mRNA Capping pathway
Gene Expression pathway
Transport of the SLBP independent Mature mRNA pathway
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs pathway
mRNA Splicing - Major Pathway pathway
Transport of Mature mRNA Derived from an Intronless Transcript pathway
Transport of Mature mRNAs Derived from Intronless Transcripts pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Transport of the SLBP Dependant Mature mRNA pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
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| KEGG |
Spliceosome pathway
RNA transport pathway
mRNA surveillance pathway pathway
Spliceosome pathway
RNA transport pathway
mRNA surveillance pathway pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | A6QNR9 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 100124428 | ||||||||||||||||||
| UniGene | Bt.77239 | ||||||||||||||||||
| RefSeq | XM_003582545 XM_003586402 | ||||||||||||||||||
| HUGO | HGNC:7658 | ||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | |||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | BC148967 DAAA02023246 | ||||||||||||||||||
| GenPept | AAI48968 | ||||||||||||||||||
| RNA Seq Atlas | 100124428 | ||||||||||||||||||