Version 5.4
Bos taurus Gene: YEATS4
Summary
InnateDB Gene IDBG-633912.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol YEATS4
Gene Name YEATS domain-containing protein 4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002256
Encoded Proteins
IDBP-685655
YEATS domain-containing protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127337:
The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:44318357-44342854
Strand Reverse strand
Band
Transcripts
ENSBTAT00000002913 ENSBTAP00000002913
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0043967 histone H4 acetylation
GO:0043968 histone H2A acetylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0035267 NuA4 histone acetyltransferase complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000127337
View Gene Order
ENSMUSG00000020171
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_172610
HATs acetylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
REACT_218274
Chromatin organization pathway
REACT_226917
HATs acetylate histones pathway
REACT_202766
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
cmyb_pathway
C-MYB transcription factor network
Cross-References
SwissProt
TrEMBL Q32LE1
UniProt Splice Variant
Entrez Gene 615330
UniGene Bt.3063
RefSeq NM_001076365
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109626 DAAA02013228 DAAA02013229
GenPept AAI09627
RNA Seq Atlas 615330

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca