InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Yeats4

Summary

InnateDB Gene

IDBG-191636.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Yeats4

Gene Name

YEATS domain containing 4

Synonyms

4930573H17Rik; B230215M10Rik; GAS41; NuBI-1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000020171

Encoded Proteins

IDBP-191638

YEATS domain containing 4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127337:
The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:117215142-117224507

Strand

Reverse strand

Band

Transcripts

ENSMUST00000020382

ENSMUSP00000020382

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	30 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008022	protein C-terminus binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0040008	regulation of growth
GO:0043967	histone H4 acetylation
GO:0043968	histone H2A acetylation

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0035267	NuA4 histone acetyltransferase complex

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000127337

View Gene Order

ENSBTAG00000002256

Not yet available

Pathways

NETPATH

REACTOME

REACT_218274

Chromatin organization pathway

REACT_226917

HATs acetylate histones pathway

REACT_202766

Chromatin modifying enzymes pathway

KEGG

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_172610

HATs acetylate histones pathway

REACT_172623

Chromatin organization pathway

REACT_172633

Chromatin modifying enzymes pathway

KEGG

INOH

PID NCI

cmyb_pathway

C-MYB transcription factor network

Cross-References

SwissProt

Q9CR11

TrEMBL

UniProt Splice Variant

Entrez Gene

64050

UniGene

Mm.233529

RefSeq

NM_026570

OMIM

CCDS

CCDS24191

HPRD

IMGT

MGI ID

MGI:1927224

MGI Symbol

Yeats4

EMBL

AK002839 AK010522 AK012096 BC020043

GenPept

AAH20043 BAB22396 BAB27003 BAB28027

RNA Seq Atlas

64050