Version 5.4
Bos taurus Gene: BT.23547
Summary
InnateDB Gene IDBG-634053.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.23547
Gene Name large proline-rich protein BAG6
Synonyms BAT3
Species Bos taurus
Ensembl Gene ENSBTAG00000019685
Encoded Proteins
IDBP-685810
HLA-B associated transcript-3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204463:
This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:27463438-27474655
Strand Forward strand
Band
Transcripts
ENSBTAT00000035789 ENSBTAP00000035657
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 109 interaction(s) predicted by orthology.
Predicted by orthology
Total 109 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030544 Hsp70 protein binding
GO:0031593 polyubiquitin binding
GO:0043022 ribosome binding
GO:0070628 proteasome binding
Biological Process
GO:0001822 kidney development
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007130 synaptonemal complex assembly
GO:0007283 spermatogenesis
GO:0007420 brain development
GO:0009790 embryo development
GO:0018393 internal peptidyl-lysine acetylation
GO:0030324 lung development
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043066 negative regulation of apoptotic process
GO:0045861 negative regulation of proteolysis
GO:0050821 protein stabilization
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071816 tail-anchored membrane protein insertion into ER membrane
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0071818 BAT3 complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000204463
View Gene Order
ENSMUSG00000024392
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.23547
RefSeq NM_001075366 XM_005223608
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca