Version 5.4
Mus musculus Gene: Bag6
Summary
InnateDB Gene IDBG-176819.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bag6
Gene Name BCL2-associated athanogene 6
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000024392
Encoded Proteins
IDBP-176821
BCL2-associated athanogene 6
IDBP-628081
BCL2-associated athanogene 6
IDBP-628082
BCL2-associated athanogene 6
IDBP-628083
BCL2-associated athanogene 6
IDBP-628084
BCL2-associated athanogene 6
IDBP-628085
BCL2-associated athanogene 6
IDBP-788191
BCL2-associated athanogene 6
IDBP-628086
BCL2-associated athanogene 6
IDBP-628087
BCL2-associated athanogene 6
IDBP-788192
BCL2-associated athanogene 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204463:
This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:35135178-35147322
Strand Forward strand
Band B1
Transcripts
ENSMUST00000025250 ENSMUSP00000025250
ENSMUST00000166426 ENSMUSP00000129324
ENSMUST00000172571 ENSMUSP00000134175
ENSMUST00000173491 ENSMUSP00000134279
ENSMUST00000173535 ENSMUSP00000133822
ENSMUST00000173952 ENSMUSP00000134717
ENSMUST00000174478 ENSMUSP00000138117
ENSMUST00000173550 ENSMUSP00000134628
ENSMUST00000174281 ENSMUSP00000134425
ENSMUST00000172889
ENSMUST00000172925
ENSMUST00000173351
ENSMUST00000174797
ENSMUST00000174613
ENSMUST00000172993 ENSMUSP00000138467
ENSMUST00000172882
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 119 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 119 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030544 Hsp70 protein binding
GO:0031593 polyubiquitin binding
GO:0043022 ribosome binding
GO:0070628 proteasome binding
Biological Process
GO:0001822 kidney development
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006810 transport
GO:0006915 apoptotic process
GO:0007130 synaptonemal complex assembly
GO:0007283 spermatogenesis
GO:0007420 brain development
GO:0009790 embryo development
GO:0016568 chromatin modification
GO:0018393 internal peptidyl-lysine acetylation
GO:0030154 cell differentiation
GO:0030324 lung development
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042127 regulation of cell proliferation
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0045861 negative regulation of proteolysis
GO:0050821 protein stabilization
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071816 tail-anchored membrane protein insertion into ER membrane
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0071818 BAT3 complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000204463
View Gene Order
ENSBTAG00000019685
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.203962 Mm.489689
RefSeq NM_001252468 NM_001252469 NM_057171 XM_006524109 XM_006524110 XM_006524111 XM_006524112 XM_006524113 XM_006524114 XM_006524115 XM_006524116 XM_006524117 XM_006524118 XM_006524119 XM_006525359 XM_006525360 XM_006525361 XM_006525362 XM_006525363 XM_006525364 XM_006525365 XM_006525366 XM_006525367 XM_006525368 XM_006525369 XM_006536580 XM_006536581 XM_006536582 XM_006536583 XM_006536584 XM_006536585 XM_006536586 XM_006536587 XM_006536588 XM_006536589 XM_006536590 XM_006537312 XM_006537313 XM_006537314 XM_006537315 XM_006537316 XM_006537317 XM_006537318 XM_006537319 XM_006537320 XM_006537321 XM_006537322
OMIM
CCDS CCDS28688 CCDS57072 CCDS57073
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca