Version 5.4
Bos taurus Gene: RRP8
Summary
InnateDB Gene IDBG-634130.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RRP8
Gene Name ribosomal RNA-processing protein 8
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000697
Encoded Proteins
IDBP-685889
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132275:
Gene Information
Type Protein coding
Genomic Location Chromosome 15:47082236-47085798
Strand Forward strand
Band
Transcripts
ENSBTAT00000039795 ENSBTAP00000039583
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0035064 methylated histone binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000183 chromatin silencing at rDNA
GO:0008152 metabolic process
GO:0032259 methylation
GO:0042149 cellular response to glucose starvation
GO:0046015 regulation of transcription by glucose
GO:0071158 positive regulation of cell cycle arrest
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
Cellular Component
GO:0005634 nucleus
GO:0005677 chromatin silencing complex
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0033553 rDNA heterochromatin
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000132275
View Gene Order
ENSMUSG00000030888
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_200827
SIRT1 negatively regulates rRNA Expression pathway
REACT_71
Gene Expression pathway
REACT_200834
Negative epigenetic regulation of rRNA expression pathway
REACT_205737
Epigenetic regulation of gene expression pathway
REACT_224328
SIRT1 negatively regulates rRNA Expression pathway
REACT_233572
Gene Expression pathway
REACT_207809
Negative epigenetic regulation of rRNA expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.45754
RefSeq NM_001192374
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca