Bos taurus Gene: TRIM3
Summary
InnateDB Gene IDBG-634193.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM3
Gene Name tripartite motif-containing protein 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003565
Encoded Proteins
tripartite motif-containing protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110171:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the \'RING-B-box-coiled-coil\' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:47193828-47219561
Strand Forward strand
Band
Transcripts
ENSBTAT00000004636 ENSBTAP00000004636
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL A7MB36
UniProt Splice Variant
Entrez Gene 534510
UniGene Bt.45458
RefSeq NM_001101157 XM_005216126 XM_005216127 XM_005216128
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151315 DAAA02040854
GenPept AAI51316
RNA Seq Atlas 534510