Bos taurus Gene: PAPOLG
Summary
InnateDB Gene IDBG-634275.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAPOLG
Gene Name poly(A) polymerase gamma
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007414
Encoded Proteins
poly(A) polymerase gamma
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115421:
This gene encodes a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3' end of a DNA/RNA strand. This enzyme shares 60% identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. This enzyme is exclusively localized in the nucleus and exhibits both nonspecific and CPSF (cleavage and polyadenylation specificity factor)/AAUAAA-dependent polyadenylation activity. This gene is located on chromosome 2 in contrast to the PAPII gene, which is located on chromosome 14. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:43378849-43408807
Strand Forward strand
Band
Transcripts
ENSBTAT00000009749 ENSBTAP00000009749
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004652 polynucleotide adenylyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006378 mRNA polyadenylation
GO:0031123 RNA 3'-end processing
GO:0043631 RNA polyadenylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
mRNA surveillance pathway pathway
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A5D7N5
UniProt Splice Variant
Entrez Gene 529071
UniGene Bt.24299
RefSeq NM_001098066
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC140625 DAAA02031008 DAAA02031009
GenPept AAI40626
RNA Seq Atlas 529071