Version 5.4
Bos taurus Gene: STXBP5
Summary
InnateDB Gene IDBG-634279.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STXBP5
Gene Name syntaxin-binding protein 5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021107
Encoded Proteins
IDBP-686075
syntaxin binding protein 5 (tomosyn)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164506:
Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:85627754-85785707
Strand Forward strand
Band
Transcripts
ENSBTAT00000061280 ENSBTAP00000053504
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017075 syntaxin-1 binding
GO:0019905 syntaxin binding
Biological Process
GO:0006887 exocytosis
GO:0010468 regulation of gene expression
GO:0016192 vesicle-mediated transport
GO:0017157 regulation of exocytosis
GO:0030193 regulation of blood coagulation
Cellular Component
GO:0005737 cytoplasm
GO:0005892 acetylcholine-gated channel complex
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000164506
View Gene Order
ENSMUSG00000019790
View Gene Order
Cross-References
SwissProt
TrEMBL E1BNK4
UniProt Splice Variant
Entrez Gene 537603
UniGene Bt.103165
RefSeq NM_001191540
HUGO HGNC:19665
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02026979 DAAA02026980 DAAA02026981 DAAA02026982 DAAA02026983
GenPept
RNA Seq Atlas 537603

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca