Version 5.4
| Bos taurus Gene: DOK2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-634459.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | DOK2 | ||||||||
| Gene Name | Docking protein 2 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000003341 | ||||||||
| Encoded Proteins |
Docking protein 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147443:
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 8:69724704-69729317 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Cell surface interactions at the vascular wall pathway
Tie2 Signaling pathway
Hemostasis pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
EGFR1 pathway
KitReceptor pathway
TCR pathway
IL3 pathway
IL4 pathway
TSLP pathway
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| REACTOME |
Tie2 Signaling pathway
Cell surface interactions at the vascular wall pathway
Hemostasis pathway
Hemostasis pathway
Cell surface interactions at the vascular wall pathway
Tie2 Signaling pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI |
IL2-mediated signaling events
Angiopoietin receptor Tie2-mediated signaling
IL4-mediated signaling events
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| Cross-References | |||||||||
| SwissProt | A7MBB8 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 514616 | ||||||||
| UniGene | Bt.2069 | ||||||||
| RefSeq | NM_001102002 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC151468 | ||||||||
| GenPept | AAI51469 | ||||||||
| RNA Seq Atlas | 514616 | ||||||||