Version 5.4
| Bos taurus Protein: DOK2 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-686246.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | DOK2 | ||||||||
| Protein Name | Docking protein 2 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000004337 | ||||||||
| InnateDB Gene | IDBG-634459 (DOK2) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | |||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR001849
Pleckstrin homology domain IPR002404 Insulin receptor substrate-1, PTB |
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| PFAM |
PF00169
PF02174 |
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| PRINTS |
PR00628
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| PIRSF | |||||||||
| SMART |
SM00233
SM00310 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | A7MBB8 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 514616 | ||||||||
| UniGene | Bt.2069 | ||||||||
| RefSeq | NP_001095472 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC151468 | ||||||||
| GenPept | AAI51469 | ||||||||