InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.92152

Summary

InnateDB Gene

IDBG-634488.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.92152

Gene Name

arachidonate 12-lipoxygenase, 12S-type

Synonyms

12-LOX

Species

Bos taurus

Ensembl Gene

ENSBTAG00000021933

Encoded Proteins

IDBP-686273

Uncharacterized protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108839:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:27421125-27434258

Strand

Forward strand

Band

Transcripts

ENSBTAT00000029240

ENSBTAP00000029240

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004052	arachidonate 12-lipoxygenase activity
GO:0005506	iron ion binding
GO:0005515	protein binding
GO:0016165	lipoxygenase activity
GO:0016491	oxidoreductase activity
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872	metal ion binding
GO:0051213	dioxygenase activity

Biological Process

GO:0006928	cellular component movement
GO:0008284	positive regulation of cell proliferation
GO:0010656	negative regulation of muscle cell apoptotic process
GO:0019369	arachidonic acid metabolic process
GO:0019372	lipoxygenase pathway
GO:0019395	fatty acid oxidation
GO:0030307	positive regulation of cell growth
GO:0030335	positive regulation of cell migration
GO:0043066	negative regulation of apoptotic process
GO:0043651	linoleic acid metabolic process
GO:0045766	positive regulation of angiogenesis
GO:0045785	positive regulation of cell adhesion
GO:0055114	oxidation-reduction process
GO:0061436	establishment of skin barrier
GO:0090331	negative regulation of platelet aggregation
GO:1901751	leukotriene A4 metabolic process
GO:2001303	lipoxin A4 biosynthetic process
GO:2001306	lipoxin B4 biosynthetic process