InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: POLR1B

Summary

InnateDB Gene

IDBG-634568.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

POLR1B

Gene Name

DNA-directed RNA polymerase I subunit RPA2

Synonyms

RPOL-1l

Species

Bos taurus

Ensembl Gene

ENSBTAG00000014166

Encoded Proteins

IDBP-686351

DNA-directed RNA polymerase I subunit RPA2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125630:
Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).[supplied by OMIM, Mar 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:46117227-46139199

Strand

Forward strand

Band

Transcripts

ENSBTAT00000018830

ENSBTAP00000018830

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.

Predicted by orthology
Total	37 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003899	DNA-directed RNA polymerase activity
GO:0005515	protein binding
GO:0016740	transferase activity
GO:0016779	nucleotidyltransferase activity
GO:0032549	ribonucleoside binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006360	transcription from RNA polymerase I promoter
GO:0007566	embryo implantation
GO:0009303	rRNA transcription
GO:0017126	nucleologenesis