Version 5.4
Bos taurus Gene: AMPH
Summary
InnateDB Gene IDBG-634592.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AMPH
Gene Name amphiphysin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000031967
Encoded Proteins
IDBP-686383
amphiphysin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000078053:
This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:83035934-83247969
Strand Forward strand
Band
Transcripts
ENSBTAT00000045324 ENSBTAP00000042723
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.
Predicted by orthology
Total 41 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005543 phospholipid binding
Biological Process
GO:0007612 learning
GO:0048488 synaptic vesicle endocytosis
Cellular Component
GO:0005737 cytoplasm
GO:0008021 synaptic vesicle
GO:0031256 leading edge membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000078053
View Gene Order
ENSMUSG00000021314
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04666
Fc gamma R-mediated phagocytosis pathway
mmu04666
Fc gamma R-mediated phagocytosis pathway
INOH
PID NCI
erbb1_internalization_pathway
Internalization of ErbB1
Cross-References
SwissProt
TrEMBL A5D783
UniProt Splice Variant
Entrez Gene 614722
UniGene Bt.107115 Bt.89279 Bt.90675
RefSeq NM_001098130 XM_005205656
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC140463 DAAA02011289 DAAA02011290 DAAA02011291 DAAA02011292
GenPept AAI40464
RNA Seq Atlas 614722

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca