InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SLC16A7

Summary

InnateDB Gene

IDBG-634779.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC16A7

Gene Name

monocarboxylate transporter 2

Synonyms

MCT2

Species

Bos taurus

Ensembl Gene

ENSBTAG00000021287

Encoded Proteins

IDBP-686569

monocarboxylate transporter 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118596:
This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:53987909-54214799

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000028361

ENSBTAP00000028361

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015129	lactate transmembrane transporter activity
GO:0015355	secondary active monocarboxylate transmembrane transporter activity
GO:0050833	pyruvate transmembrane transporter activity

Biological Process

GO:0015711	organic anion transport
GO:0015718	monocarboxylic acid transport
GO:0035873	lactate transmembrane transport
GO:0055085	transmembrane transport
GO:1901475	pyruvate transmembrane transport