Version 5.4
Homo sapiens Gene: TBC1D25
Summary
InnateDB Gene IDBG-63480.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBC1D25
Gene Name TBC1 domain family, member 25
Synonyms MG81; OATL1
Species Homo sapiens
Ensembl Gene ENSG00000068354
Encoded Proteins
IDBP-63484
TBC1 domain family, member 25
IDBP-370346
TBC1 domain family, member 25
IDBP-811526
TBC1 domain family, member 25
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with a TBC domain and may function as a Rab GTPase activating protein. This gene was previously known as ornithine aminotransferase-like 1, but has no similarity to ornithine aminotransferase. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:48539457-48562609
Strand Forward strand
Band p11.23
Transcripts
ENST00000376771 ENSP00000365962
ENST00000418627 ENSP00000402268
ENST00000481090 ENSP00000476787
ENST00000494495
ENST00000476141
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
GO:0005515 protein binding
GO:0008483 transaminase activity
Biological Process
GO:0006914 autophagy
GO:0008152 metabolic process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
GO:1901096 regulation of autophagic vacuole maturation
Cellular Component
GO:0005776 autophagic vacuole
GO:0031410 cytoplasmic vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039201
View Gene Order
ENSBTAG00000009288
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.694353
RefSeq NM_002536
HUGO
OMIM
CCDS CCDS35242
HPRD 08948
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca