Version 5.4
Bos taurus Gene: BT.49540
Summary
InnateDB Gene IDBG-634860.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.49540
Gene Name short-chain specific acyl-CoA dehydrogenase, mitochondrial precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007484
Encoded Proteins
IDBP-686671
short-chain specific acyl-CoA dehydrogenase, mitochondrial precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122971:
This gene encodes a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:65220605-65237484
Strand Forward strand
Band
Transcripts
ENSBTAT00000009844 ENSBTAP00000009844
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003995 acyl-CoA dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000122971
View Gene Order
ENSMUSG00000029545
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1887
Beta oxidation of hexanoyl-CoA to butanoyl-CoA pathway
REACT_419
Beta oxidation of butanoyl-CoA to acetyl-CoA pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_1473
Mitochondrial Fatty Acid Beta-Oxidation pathway
REACT_1541
mitochondrial fatty acid beta-oxidation of saturated fatty acids pathway
REACT_111217
Metabolism pathway
REACT_256522
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_233858
Mitochondrial Fatty Acid Beta-Oxidation pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_257646
mitochondrial fatty acid beta-oxidation of saturated fatty acids pathway
REACT_256910
Beta oxidation of hexanoyl-CoA to butanoyl-CoA pathway
REACT_231111
Beta oxidation of butanoyl-CoA to acetyl-CoA pathway
KEGG
hsa00280
Valine, leucine and isoleucine degradation pathway
hsa00650
Butanoate metabolism pathway
hsa00071
Fatty acid degradation pathway
mmu00280
Valine, leucine and isoleucine degradation pathway
mmu00650
Butanoate metabolism pathway
mmu00071
Fatty acid degradation pathway
INOH
INOH website
Butanoate metabolism pathway
INOH website
Valine Leucine Isoleucine degradation pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.49540
RefSeq NM_001034401 XM_005217788
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca