Version 5.4
Bos taurus Gene: BT.59273
Summary
InnateDB Gene IDBG-634879.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.59273
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016338
Encoded Proteins
IDBP-686715
Uncharacterized protein
IDBP-686716
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 26851218
[Mus musculus] Sppl3 is an intramembrane aspartyl protease that controls natural killer cell maturation and cytotoxicity.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157837:
Gene Information
Type Protein coding
Genomic Location Chromosome 17:65280174-65310143
Strand Reverse strand
Band
Transcripts
ENSBTAT00000065435 ENSBTAP00000053963
ENSBTAT00000021732 ENSBTAP00000021732
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004190 aspartic-type endopeptidase activity
GO:0042500 aspartic endopeptidase activity, intramembrane cleaving
GO:0042803 protein homodimerization activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005791 rough endoplasmic reticulum
GO:0016021 integral component of membrane
GO:0030660 Golgi-associated vesicle membrane
GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000157837
View Gene Order
ENSMUSG00000029550
View Gene Order
Cross-References
SwissProt
TrEMBL G3MWR0
UniProt Splice Variant
Entrez Gene 535156
UniGene
RefSeq XM_002694525 XM_615162
HUGO HGNC:30424
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02045457
GenPept
RNA Seq Atlas 535156

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca