Version 5.4
Bos taurus Gene: KDM3A
Summary
InnateDB Gene IDBG-634953.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KDM3A
Gene Name lysine-specific demethylase 3A
Synonyms JMJD1A
Species Bos taurus
Ensembl Gene ENSBTAG00000013580
Encoded Proteins
IDBP-686773
lysine (K)-specific demethylase 3A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115548:
This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:48248720-48304335
Strand Reverse strand
Band
Transcripts
ENSBTAT00000018069 ENSBTAP00000018069
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0001047 core promoter binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0050681 androgen receptor binding
Biological Process
GO:0007283 spermatogenesis
GO:0007290 spermatid nucleus elongation
GO:0009755 hormone-mediated signaling pathway
GO:0030521 androgen receptor signaling pathway
GO:0033169 histone H3-K9 demethylation
GO:0036123 histone H3-K9 dimethylation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046293 formaldehyde biosynthetic process
GO:0051573 negative regulation of histone H3-K9 methylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000115548
View Gene Order
ENSMUSG00000053470
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
REACT_228178
HDMs demethylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
REACT_218274
Chromatin organization pathway
REACT_256030
HDMs demethylate histones pathway
REACT_202766
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
ar_pathway
Coregulation of Androgen receptor activity
Cross-References
SwissProt
TrEMBL E1BFC2
UniProt Splice Variant
Entrez Gene 536073
UniGene Bt.106262 Bt.52403
RefSeq NM_001192872 XM_005212788 XM_005212790
HUGO HGNC:20815
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02031122
GenPept
RNA Seq Atlas 536073

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca