Bos taurus Gene: FBXO5 | |||||||||||||||||||||
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Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-634973.2 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | FBXO5 | ||||||||||||||||||||
Gene Name | F-box only protein 5 | ||||||||||||||||||||
Synonyms | |||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||
Ensembl Gene | ENSBTAG00000021193 | ||||||||||||||||||||
Encoded Proteins |
F-box only protein 5
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Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112029:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Dec 2008] |
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Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 9:91056939-91067416 | ||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||
Band | |||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||
NETPATH | |||||||||||||||||||||
REACTOME |
SCF-beta-TrCP mediated degradation of Emi1 pathway
Phosphorylation of Emi1 pathway
Regulation of APC/C activators between G1/S and early anaphase pathway
Mitotic Metaphase/Anaphase Transition pathway
G1/S-Specific Transcription pathway
E2F mediated regulation of DNA replication pathway
APC/C-mediated degradation of cell cycle proteins pathway
Regulation of mitotic cell cycle pathway
Mitotic G1-G1/S phases pathway
G1/S Transition pathway
Cell Cycle pathway
M Phase pathway
Cell Cycle, Mitotic pathway
Mitotic Metaphase and Anaphase pathway
Cell Cycle, Mitotic pathway
Phosphorylation of Emi1 pathway
Cell Cycle pathway
APC/C-mediated degradation of cell cycle proteins pathway
M Phase pathway
SCF-beta-TrCP mediated degradation of Emi1 pathway
Regulation of APC/C activators between G1/S and early anaphase pathway
Regulation of mitotic cell cycle pathway
Mitotic Metaphase and Anaphase pathway
G1/S Transition pathway
Mitotic Metaphase/Anaphase Transition pathway
Mitotic G1-G1/S phases pathway
G1/S-Specific Transcription pathway
E2F mediated regulation of DNA replication pathway
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KEGG |
Oocyte meiosis pathway
Oocyte meiosis pathway
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INOH | |||||||||||||||||||||
PID NCI |
PLK1 signaling events
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Cross-References | |||||||||||||||||||||
SwissProt | |||||||||||||||||||||
TrEMBL | |||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
UniGene | Bt.986 | ||||||||||||||||||||
RefSeq | NM_001082435 | ||||||||||||||||||||
HUGO | |||||||||||||||||||||
OMIM | |||||||||||||||||||||
CCDS | |||||||||||||||||||||
HPRD | |||||||||||||||||||||
IMGT | |||||||||||||||||||||
EMBL | |||||||||||||||||||||
GenPept | |||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||