Version 5.4
Bos taurus Gene: MARS
Summary
InnateDB Gene IDBG-635164.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MARS
Gene Name methionyl-tRNA synthetase, cytoplasmic
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018405
Encoded Proteins
IDBP-687002
methionyl-tRNA synthetase, cytoplasmic
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166986:
This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:56289163-56307931
Strand Reverse strand
Band
Transcripts
ENSBTAT00000024487 ENSBTAP00000024487
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004825 methionine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006431 methionyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000166986
View Gene Order
ENSMUSG00000040354
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15306
Cytosolic tRNA aminoacylation pathway
REACT_15482
tRNA Aminoacylation pathway
REACT_71
Gene Expression pathway
KEGG
hsa00450
Selenocompound metabolism pathway
hsa00970
Aminoacyl-tRNA biosynthesis pathway
mmu00970
Aminoacyl-tRNA biosynthesis pathway
mmu00450
Selenocompound metabolism pathway
INOH
INOH website
Methionine Cysteine metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL F1MDW1
UniProt Splice Variant
Entrez Gene 512531
UniGene Bt.9306
RefSeq NM_001038091 XM_005206572
HUGO HGNC:6898
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02013500
GenPept
RNA Seq Atlas 512531

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca