Version 5.4
Bos taurus Gene: SERAC1
Summary
InnateDB Gene IDBG-635259.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERAC1
Gene Name Protein SERAC1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011509
Encoded Proteins
IDBP-687093
Protein SERAC1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122335:
The protein encoded by this gene is a phosphatidylglycerol remodeling protein found at the interface of mitochondria and endoplasmic reticula, where it mediates phospholipid exchange. The encoded protein plays a major role in mitochondrial function and intracellular cholesterol trafficking. Defects in this gene are a cause of 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (MEGDEL). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:96101795-96140851
Strand Reverse strand
Band
Transcripts
ENSBTAT00000015295 ENSBTAP00000015295
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0006505 GPI anchor metabolic process
GO:0006629 lipid metabolic process
GO:0006886 intracellular protein transport
GO:0008654 phospholipid biosynthetic process
GO:0030198 extracellular matrix organization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000122335
View Gene Order
ENSMUSG00000015659
View Gene Order
Cross-References
SwissProt Q2TBM9
TrEMBL
UniProt Splice Variant
Entrez Gene 519860
UniGene Bt.87758
RefSeq NM_001038550 XM_005211072
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109896
GenPept AAI09897
RNA Seq Atlas 519860

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca