Bos taurus Gene: CKB
Summary
InnateDB Gene IDBG-635454.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CKB
Gene Name Creatine kinase B-type
Synonyms B-CK
Species Bos taurus
Ensembl Gene ENSBTAG00000035998
Encoded Proteins
Creatine kinase B-type
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166165:
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:69809416-69812653
Strand Reverse strand
Band
Transcripts
ENSBTAT00000050490 ENSBTAP00000047181
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0004111 creatine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007420 brain development
GO:0016310 phosphorylation
GO:0021762 substantia nigra development
GO:0030644 cellular chloride ion homeostasis
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Metabolism of amino acids and derivatives pathway
Creatine metabolism pathway
Metabolism pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Creatine metabolism pathway
Metabolism of amino acids and derivatives pathway
Metabolism pathway
Creatine metabolism pathway
Metabolism pathway
Metabolism of amino acids and derivatives pathway
KEGG
Arginine and proline metabolism pathway
Arginine and proline metabolism pathway
INOH
Arginine Proline metabolism pathway
PID NCI
Cross-References
SwissProt Q5EA61
TrEMBL Q9N1C7
UniProt Splice Variant
Entrez Gene 516210
UniGene Bt.5084 Bt.88935
RefSeq NM_001015613 XM_003583773
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF207866 BC102333 BT020708
GenPept AAF67082 AAI02334 AAX08725
RNA Seq Atlas 100851864 516210