Version 5.4
Bos taurus Gene: BT.105016
Summary
InnateDB Gene IDBG-635487.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.105016
Gene Name cadherin EGF LAG seven-pass G-type receptor 2 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018804
Encoded Proteins
IDBP-687342
Uncharacterized protein
IDBP-687347
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143126:
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:34246149-34270501
Strand Reverse strand
Band
Transcripts
ENSBTAT00000063317 ENSBTAP00000054420
ENSBTAT00000025033 ENSBTAP00000025033
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0001764 neuron migration
GO:0003341 cilium movement
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0021591 ventricular system development
GO:0032880 regulation of protein localization
GO:0033326 cerebrospinal fluid secretion
GO:0042384 cilium assembly
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000143126
View Gene Order
ENSMUSG00000068740
View Gene Order
Cross-References
SwissProt
TrEMBL G3MXZ5
UniProt Splice Variant
Entrez Gene 538194
UniGene Bt.105016 Bt.42980
RefSeq NM_001192931
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02007576
GenPept
RNA Seq Atlas 538194

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca