Version 5.4
| Bos taurus Gene: GNRH1 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-635529.3 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | GNRH1 | ||||||||||||
| Gene Name | progonadoliberin-1 precursor | ||||||||||||
| Synonyms | |||||||||||||
| Species | Bos taurus | ||||||||||||
| Ensembl Gene | ENSBTAG00000000164 | ||||||||||||
| Encoded Proteins |
progonadoliberin-1
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| Protein Structure | |||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147437:
The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2012] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 8:73698976-73702769 | ||||||||||||
| Strand | Reverse strand | ||||||||||||
| Band | |||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Hormone ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Hormone ligand-binding receptors pathway
GPCR ligand binding pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
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| KEGG |
GnRH signaling pathway pathway
GnRH signaling pathway pathway
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| INOH |
GPCR signaling pathway
GPCR signaling pathway
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| PID NCI |
Nongenotropic Androgen signaling
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| Cross-References | |||||||||||||
| SwissProt | |||||||||||||
| TrEMBL | Q0VBW7 | ||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 768325 | ||||||||||||
| UniGene | Bt.74220 | ||||||||||||
| RefSeq | NM_001078137 | ||||||||||||
| HUGO | |||||||||||||
| OMIM | |||||||||||||
| CCDS | |||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| EMBL | BC120472 DAAA02023655 | ||||||||||||
| GenPept | AAI20473 | ||||||||||||
| RNA Seq Atlas | 768325 | ||||||||||||