Version 5.4
| Bos taurus Gene: PDPK1 | |||||||||||||||||||||||||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||||||||||||||||||||||||
| InnateDB Gene | IDBG-635536.3 | ||||||||||||||||||||||||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||||||||||||||||||||||
| Gene Symbol | PDPK1 | ||||||||||||||||||||||||||||||||||||||||||||
| Gene Name | Uncharacterized protein | ||||||||||||||||||||||||||||||||||||||||||||
| Synonyms | |||||||||||||||||||||||||||||||||||||||||||||
| Species | Bos taurus | ||||||||||||||||||||||||||||||||||||||||||||
| Ensembl Gene | ENSBTAG00000034436 | ||||||||||||||||||||||||||||||||||||||||||||
| Encoded Proteins |
3-phosphoinositide dependent protein kinase-1
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| Protein Structure | |||||||||||||||||||||||||||||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140992:
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| Gene Information | |||||||||||||||||||||||||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||||||||||||||||||||||||
| Genomic Location | Chromosome 25:2062819-2097196 | ||||||||||||||||||||||||||||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||||||||||||||||||||||||||||
| Band | |||||||||||||||||||||||||||||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||||||||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 70 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||||||||||||||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||||||||||||||||||||||
| NETPATH |
EGFR1 pathway
TGF_beta_Receptor pathway
BCR pathway
TSH pathway
IL11 pathway
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| REACTOME |
PIP3 activates AKT signaling pathway
DAP12 signaling pathway
DAP12 interactions pathway
Downstream TCR signaling pathway
CTLA4 inhibitory signaling pathway
CD28 dependent PI3K/Akt signaling pathway
CD28 co-stimulation pathway
Costimulation by the CD28 family pathway
Integrin alphaIIb beta3 signaling pathway
Platelet Aggregation (Plug Formation) pathway
GPVI-mediated activation cascade pathway
PI3K/AKT activation pathway
Activation of PKB pathway
GAB1 signalosome pathway
Signaling by EGFR pathway
G beta:gamma signalling through PI3Kgamma pathway
PI3K events in ERBB4 signaling pathway
Signaling by ERBB4 pathway
PI3K Cascade pathway
Signaling by Insulin receptor pathway
IRS-related events triggered by IGF1R pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
PI3K events in ERBB2 signaling pathway
Signaling by ERBB2 pathway
PI-3K cascade pathway
Signaling by FGFR pathway
Signaling by SCF-KIT pathway
Downstream signal transduction pathway
Signaling by PDGF pathway
Constitutive PI3K/AKT Signaling in Cancer pathway
RSK activation pathway
CREB phosphorylation through the activation of Ras pathway
Signaling by FGFR in disease pathway
FCERI mediated NF-kB activation pathway
Signalling by NGF pathway
Signaling by EGFR in Cancer pathway
Downstream signaling of activated FGFR pathway
TCR signaling pathway
Neuronal System pathway
Signaling by VEGF pathway
Role of LAT2/NTAL/LAB on calcium mobilization pathway
Signaling by GPCR pathway
Innate Immune System pathway
Platelet activation, signaling and aggregation pathway
VEGFR2 mediated vascular permeability pathway
G-protein beta:gamma signalling pathway
Fc epsilon receptor (FCERI) signaling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Post NMDA receptor activation events pathway
IRS-mediated signalling pathway
Adaptive Immune System pathway
Immune System pathway
VEGFR2 mediated cell proliferation pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events pathway
Insulin receptor signalling cascade pathway
VEGFA-VEGFR2 Pathway pathway
NGF signalling via TRKA from the plasma membrane pathway
IRS-related events pathway
Transmission across Chemical Synapses pathway
IGF1R signaling cascade pathway
PI3K/AKT Signaling in Cancer pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Signaling by the B Cell Receptor (BCR) pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
Disease pathway
Hemostasis pathway
Innate Immune System pathway
Signaling by the B Cell Receptor (BCR) pathway
Signaling by ERBB2 pathway
GPCR downstream signaling pathway
PI3K/AKT activation pathway
CD28 dependent PI3K/Akt signaling pathway
Disease pathway
Hemostasis pathway
Signaling by GPCR pathway
Signaling by Insulin receptor pathway
Downstream TCR signaling pathway
Signaling by VEGF pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Signaling by FGFR in disease pathway
Signaling by ERBB4 pathway
Signaling by SCF-KIT pathway
FCERI mediated NF-kB activation pathway
VEGFR2 mediated cell proliferation pathway
Activation of PKB pathway
PIP3 activates AKT signaling pathway
CREB phosphorylation through the activation of Ras pathway
Immune System pathway
Platelet activation, signaling and aggregation pathway
Post NMDA receptor activation events pathway
Downstream signal transduction pathway
Downstream signaling of activated FGFR pathway
Constitutive PI3K/AKT Signaling in Cancer pathway
PI3K events in ERBB4 signaling pathway
PI-3K cascade pathway
Signaling by EGFR pathway
GPVI-mediated activation cascade pathway
Insulin receptor signalling cascade pathway
IRS-related events triggered by IGF1R pathway
IGF1R signaling cascade pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
CD28 co-stimulation pathway
Costimulation by the CD28 family pathway
Role of LAT2/NTAL/LAB on calcium mobilization pathway
VEGFR2 mediated vascular permeability pathway
PI3K Cascade pathway
VEGFA-VEGFR2 Pathway pathway
Fc epsilon receptor (FCERI) signaling pathway
PI3K/AKT Signaling in Cancer pathway
CTLA4 inhibitory signaling pathway
Signalling by NGF pathway
Adaptive Immune System pathway
Signaling by PDGF pathway
Neuronal System pathway
GAB1 signalosome pathway
IRS-related events pathway
NGF signalling via TRKA from the plasma membrane pathway
IRS-mediated signalling pathway
G-protein beta:gamma signalling pathway
PI3K events in ERBB2 signaling pathway
Signal Transduction pathway
Integrin alphaIIb beta3 signaling pathway
G beta:gamma signalling through PI3Kgamma pathway
Transmission across Chemical Synapses pathway
Signaling by FGFR pathway
Platelet Aggregation (Plug Formation) pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events pathway
RSK activation pathway
TCR signaling pathway
Signaling by EGFR in Cancer pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
DAP12 interactions pathway
DAP12 signaling pathway
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| KEGG |
mTOR signaling pathway pathway
Fc epsilon RI signaling pathway pathway
Non-small cell lung cancer pathway
Endometrial cancer pathway
Insulin signaling pathway pathway
Prostate cancer pathway
Focal adhesion pathway
T cell receptor signaling pathway pathway
PPAR signaling pathway pathway
Neurotrophin signaling pathway pathway
Aldosterone-regulated sodium reabsorption pathway
Toxoplasmosis pathway
Hepatitis C pathway
Endometrial cancer pathway
Insulin signaling pathway pathway
T cell receptor signaling pathway pathway
PPAR signaling pathway pathway
Fc epsilon RI signaling pathway pathway
mTOR signaling pathway pathway
Prostate cancer pathway
Non-small cell lung cancer pathway
Focal adhesion pathway
Neurotrophin signaling pathway pathway
Aldosterone-regulated sodium reabsorption pathway
Toxoplasmosis pathway
Hepatitis C pathway
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| INOH |
CD4 T cell receptor signaling pathway
IL-7 signaling pathway
JAK STAT pathway and regulation pathway
EPO signaling pathway pathway
Insulin receptor signaling pathway
VEGF signaling pathway pathway
IGF1 signaling pathway pathway
PDGF signaling pathway pathway
CD4 T cell receptor signaling pathway
IL-7 signaling pathway
JAK STAT pathway and regulation pathway
EPO signaling pathway pathway
Insulin receptor signaling pathway
VEGF signaling pathway pathway
PDGF signaling pathway pathway
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| PID NCI |
Trk receptor signaling mediated by PI3K and PLC-gamma
TCR signaling in naïve CD8+ T cells
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
Class I PI3K signaling events
IL8- and CXCR2-mediated signaling events
Class I PI3K signaling events mediated by Akt
CXCR4-mediated signaling events
IL8- and CXCR1-mediated signaling events
TCR signaling in naïve CD4+ T cells
ErbB1 downstream signaling
mTOR signaling pathway
IGF1 pathway
FGF signaling pathway
BCR signaling pathway
Signaling events mediated by Stem cell factor receptor (c-Kit)
Signaling events mediated by VEGFR1 and VEGFR2
TGF-beta receptor signaling
CXCR3-mediated signaling events
VEGFR1 specific signals
Insulin Pathway
FAS (CD95) signaling pathway
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| Cross-References | |||||||||||||||||||||||||||||||||||||||||||||
| SwissProt | |||||||||||||||||||||||||||||||||||||||||||||
| TrEMBL | F1MQJ7 | ||||||||||||||||||||||||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||||||||||||||||||||||||
| Entrez Gene | 100138102 | ||||||||||||||||||||||||||||||||||||||||||||
| UniGene | |||||||||||||||||||||||||||||||||||||||||||||
| RefSeq | XM_002697862 | ||||||||||||||||||||||||||||||||||||||||||||
| HUGO | HGNC:8816 | ||||||||||||||||||||||||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||||||||||||||||||||||||
| CCDS | |||||||||||||||||||||||||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||||||||||||||||||||||||
| EMBL | DAAA02057316 | ||||||||||||||||||||||||||||||||||||||||||||
| GenPept | |||||||||||||||||||||||||||||||||||||||||||||
| RNA Seq Atlas | 100138102 | ||||||||||||||||||||||||||||||||||||||||||||