Version 5.4
Homo sapiens Gene: CHST10
Summary
InnateDB Gene IDBG-63565.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHST10
Gene Name carbohydrate sulfotransferase 10
Synonyms HNK-1ST; HNK1ST
Species Homo sapiens
Ensembl Gene ENSG00000115526
Encoded Proteins
IDBP-63567
carbohydrate sulfotransferase 10
IDBP-295157
carbohydrate sulfotransferase 10
IDBP-295156
carbohydrate sulfotransferase 10
IDBP-383638
carbohydrate sulfotransferase 10
IDBP-383640
carbohydrate sulfotransferase 10
IDBP-383641
carbohydrate sulfotransferase 10
IDBP-383644
carbohydrate sulfotransferase 10
IDBP-383645
carbohydrate sulfotransferase 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This protein encoded by this gene transfers sulfate to the C-3 hydroxyl of terminal glucuronic acid of protein- and lipid-linked oligosaccharides. This protein was first identified as a sulfotransferase that acts on the human natural killer-1 (HNK-1) glycan; HNK-1 is a carbohydrate involved in neurodevelopment and synaptic plasticity.[provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:100391860-100417656
Strand Reverse strand
Band q11.2
Transcripts
ENST00000264249 ENSP00000264249
ENST00000409701 ENSP00000387309
ENST00000409046 ENSP00000387121
ENST00000420858 ENSP00000405922
ENST00000448989 ENSP00000387977
ENST00000421474 ENSP00000407525
ENST00000418201 ENSP00000416831
ENST00000435960 ENSP00000395643
ENST00000484382
ENST00000485085
ENST00000487860
ENST00000466583
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008146 sulfotransferase activity
GO:0016232 HNK-1 sulfotransferase activity
Biological Process
GO:0007155 cell adhesion
GO:0007612 learning
GO:0007616 long-term memory
GO:0016051 carbohydrate biosynthetic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026080
View Gene Order
ENSBTAG00000004328
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00514
Other types of O-glycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.516370 Hs.595646
RefSeq NM_004854
HUGO
OMIM
CCDS CCDS2047
HPRD 07332
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca